MCQs: Sterility & Pyrogen Testing

Multiple Choice Questions: Sterility & Pyrogen Testing

MCQs: Sterility & Pyrogen Testing

Quiz

  

Atttempt as many times u like within 45 minutes.

 

1. As per I.P. temperature range for incubation in Sterility testing is,
   1.   20-25 ℃
   2.   25-30 ℃
   3.   30-35 ℃
   4.   35-40 ℃
2. Which of the following tests is conducted to ensure that the parenteral product is completely free from microorganisms.
   1.   Sterility testing.
   2.   Pyrogen Testing.
   3.   Clarity testing.
   4.   Leakage Testing.
3. Which of the following tests is conducted to ensure that the parenteral product is completely free from fever inducing substances.
   1.   Sterility testing
   2.   Pyrogen Testing
   3.   Clarity testing
   4.   Clarity Testing
4. Which of the following substances is used as an inactivating agent for “Penicillin”.
   1.   Penicillinase
   2.   Cephalosporinase
   3.   Penicillamine
   4.   Acetyl Transferase
5. Which of the following substances is used as an inactivating agent for “Cephalosporins”.
   1.   Penicillinase
   2.   Cephalosporinase
   3.   Penicillamine
   4.   Acetyl Transferase.
6. Which of the following substances is used as an inactivating agent for “Chloramphenicol”.
   1.   Penicillinase
   2.   Cephalosporinase
   3.   Penicillamine
   4.   Acetyl Transferase
7. Which of the following substances is used as an inactivating agent for “Sulfonamides”.
   1.   Penicillinase
   2.   PABA (Para Amino Benzoic Acid)
   3.   Penicillamine
   4.   Acetyl Transferase
8. Which of the following substances is used as an inactivating agent for “Heavy Metals”.
   1.   Thioglycolic Acid
   2.   Cephalosporinase
   3.   Penicillamine
   4.   Acetyl Transferase
9. Which of the following substances is used as an inactivating agent for “Aminoglycosides”.
   1.   Penicillinase
   2.   Acetyl Coenzyme A
   3.   Penicillamine
   4.   Acetyl Transferase.
10. Which of the following substances is used as an inactivating agent for “Phenols”.
    1.   Dilution
    2.   Lecithin + Tween 80
    3.   PABA
    4.   Acetyl Transferase
11. Which of the following substances is used as an inactivating agent for “Quaternary Ammonium Compounds”.
    1.   Dilution
    2.   Lecithin + Tween 80
    3.   PABA
    4.   Acetyl Transferase
12. Which of the following culture mediums is used to detect fungi in sterility testings.
    1.   Alternative Thioglycollate Medium (ATM)
    2.   Fluid Thioglycollate Medium (FTM)
    3.   Soybean Casein Digest Medium (SCDM)
    4.   Stuart’s medium
13. Which of the following culture mediums is used to detect exclusively anaerobic bacteria in sterility testings.
    1.   Alternative Thioglycollate Medium (ATM)
    2.   Fluid Thioglycollate Medium (FTM)
    3.   Soybean Casein Digest Medium (SCDM)
    4.   Stuart’s medium
14. Which of the following culture mediums contains an indicator “Resazurin”.
    1.   Alternative Thioglycollate Medium (ATM)
    2.   Fluid Thioglycollate Medium (FTM)
    3.   Soybean Casein Digest Medium (SCDM)
    4.   Stuart’s medium
15. Which of the following microorganisms is used as a test microorganism in Growth Promotion Test of Fluid Thioglycollate Media (FTM).
    1.   Bacillus subtilis
    2.   Candida albicans
    3.   Clostridium sporogenes
    4.   Bacteroides vulgatus
16. Which of the following microorganisms is used as a test microorganism in Growth Promotion Test of Alternative Thioglycollate Media (ATM).
    1.   Pseudomonas aeruginosa
    2.   Candida albicans.
    3.   Clostridium sporogenes
    4.   Staphylococcus aureus
17. Which of the following microorganisms is used as a test microorganism in the Growth Promotion Test of Soyabean Casein Digest Media (SCDM).
    1.   Bacillus subtilis
    2.   Candida albicans
    3.   Clostridium sporogenes
    4.   Bacteroides vulgatus
18. Which of the following membranes is used to filter the parenterals containing strong alcoholic solutions during sterility testing.
    1.   Cellulose acetate
    2.   Cellulose nitrate
19. Which of the following membranes is used to filter the parenterals containing oily solutions during sterility testing.
    1.   Cellulose acetate
    2.   Cellulose nitrate
20. Which dilution medium is used for parenterals containing oily substances.
    1.   Fluid A
    2.   Fluid B
21. While conducting a Retest of Rabbits Test for Pyrogens there should not be cumulative rise of ------- in Rabbits body Temperatures.
    1.   1.4℃
    2.   2.4℃
    3.   3.7℃
    4.   2.8℃
22. While conducting a Rabbits Test for Pyrogens there should not be a cumulative rise of ------- in Rabbits body Temperatures.
    1.   1.4℃
    2.   2.4℃
    3.   3.7℃
    4.   3.7℃
23. LAL (Limulus Amebocyte Lysate)Test is also called,
    1.   Bacterial Endotoxin Test
    2.   Bacterial Exotoxin Test
    3.   Bacterial Spore Test
    4.   Bacterial Infection Test