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Renin Angiotensin Mechanism.

Important Drugs and their active Isomers.

Important Drugs and their active Isomers.

  • GPAT and other exams always ask at least one question regarding the subject stated above, this is an effort to bring important drugs together for easy study.
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Name of drug
Stereospecific isomer
Ethambutol                                                   
Dextro isomer is 16 times more active than meso
Cyclophosphamide                                             
Levo form has twice activity than D form
Chloprothixene
Z isomer is more active
Doxepin HCL
Z isomer is more active
Lysergic acid diethyl amide 
Dextro is active
Epinephrine 
Levo form is active
Pseudoephedrine
(+) threo isomer
Propranolol
Only levo isomer is a potent beta antagonist
Hyoscyamine
Levo isomer
Atropine 
Racemic mixture
Captopril
S isomer is active
Sulindac
Z isomer
Ibuprofen
(s) – (+) isomer
Ephedrine
(-) erythro is active
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